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Tolu balsam is a sap-like substance that comes from the Myroxylon balsamum tree. 303. Tolu balsam is best known for its fragrance and use as flavoring in pharmaceutical products, although it also has mild antiseptic and expectorant properties. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. 0. The oily sap from the bark is used to make medicine. Oil distilled from the wood is about 70% nerolidol. Traditional dosage of the herb for colds has been 0.6 g daily. You should talk with your health care provider for complete information about the risks and benefits of using this product. pereirae (Royle) Harms.Common Name(s): Balsam of Peru, Balsamo blanco, Baumier du Perou, Black balsam, Indian balsam, Peru balsam, Perubalsambaum, Peruvian balsam. This gum has a long history of use by local people as a medicine and is also widely used in modern herbal medicine, as an incense, perfume ingredient etc [. There are no clinical data to support its use in any condition. 0. Additional patch testing is recommended in Peru balsam–sensitive individuals to trace the origins of sensitization.Hausen 2001, Srivastava 2009 As a basic screening tool to improve detection and management of allergic contact eyelid dermatitis cases, balsam of Peru 25% in petrolatum has been recommended as a standard patch-test component based on data supporting its high frequency as a relevant antigen.Herro 2012, The importance of recognizing food items that contain balsam of Peru-associated constituents was highlighted in a case series of 7 children with systemic manifestations of recalcitrant dermatitis. We comply with the HONcode standard for trustworthy health information -. In addition, traces of styrene, vanillin, and coumarin have been identified in the material. However, there are no animal or clinical studies to support its use for any condition. This is only a brief summary of general information about this product. It can be applied to the chest to relieve asthma, colds, coughs and bronchitis. It is insoluble in water, but soluble in pharmaceutical solvents such as alcohol, ether, sodium hydroxide solution, and chloroform. Equivocal data prevented an association being made with atopic vs non-atopic individuals.Rodrigues 2016 It may cause dermatitis in individuals who have a sensitivity to benzoin resinoids. Tolu balsam is applied directly to the skin to treat bedsores, cracked nipples, cracked lips, and minor skin cuts. Peru balsam has been used topically in 5% to 20% formulations for wounds and burns. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. When diluted in carrier oil, balsam of Peru oil may relieve dry chapped skin, eczema, rashes, sores and wounds, rheumatism, diaper rash, bedsores, pruritus, prurigo, and sore nipples. Cross-reactivity with naturally occurring sources of similar chemicals has been reported with orange peel, clove, and tomatoes. The volatile oil primarily contains benzyl cinnamate and other benzoic and cinnamic acid esters, with small amounts of benzyl alcohol and related compounds. The 5 foods listed on the avoidance list for the low balsam of Peru diet were tomatoes and tomato-containing products, peels of citrus fruits, chocolate, cola and spiced sodas, and cinnamon, cloves, and vanilla.Herro 2013 Similarly, initiation of a low balsam of Peru diet improved pruritic allergic dermatitis symptoms in a 48-year-old man within 1 month of dietary changes, which was sustained for several months.Nanda 2016 Cases of cheilitis and perioral dermatitis have been reported in 2 individuals who used Lucas Papaw ointment, which included small amounts of Myroxylon pereirae that was not listed as an ingredient on the labeling but was later confirmed by the manufacturer.Tan 2011. They also used the material as a diuretic and to expel worms. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Therapeutic uses. The plant is the only species within the genus Myroxylon; however, there are 2 varieties, var. Information regarding safety and efficacy in pregnancy and lactation is lacking. It is an ingredient in compound benzoin tincture used in the treatment of bedsores, cracked skin, and minor cuts. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Contraindications have not yet been determined. The plant is the only species within the genus Myroxylon; however, there are 2 varieties, var. The material is not used internally. Information regarding safety and efficacy in pregnancy and lactation is lacking. This is only a brief summary of general information about this product. Instituting a low balsam of Peru diet that included avoidance of ketchup achieved 80% improvement in 5 of the 7 children, 70% in the 6th child, and 60% improvement in the 7th. Systemic toxicity following application of Peru balsam to the nipples of breast-feeding mothers has been reported.Duke 2002, Peru balsam is a contact allergen, and contact dermatitis occurs frequently with the product.Balato 2011, Krob 2004, Nijhawan 2009, Thyssen 2009 In a systematic review of 34 studies covering a 15-year period, it was found to be among the top 10 most common allergens in adolescents and a less common antigen in children. This information relates to an herbal, vitamin, mineral or other dietary supplement. The balsam contains up to 80% resin, approximately 15% free cinnamic acid and benzoic acid, and about 40% of the benzyl and related esters of these free acids. A wide variety of additional minor components have been identified in the balsam. Formerly, it was used widely as a treatment for scabies; it has also been used in suppositories for hemorrhoids and in dentistry in the treatment of dry socket (postextraction alveolitis) and as a component of dental impression material. Cross-reactivity with food sources that naturally contain chemicals similar to the volatile oils and resins in balsam of Peru include orange peel, clove, and tomatoes. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Peru balsam has been used in the treatment of dry socket in dentistry, topically as a treatment for wounds and ulcers, and in suppositories for hemorrhoids. Today, the material is in a number of pharmaceutical preparations and plays an important role in perfumery. The best form of the gum is generally considered to come from the var Myroxylon balsamum pereirae (see separate entry). Medically reviewed by Drugs.com. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Tolu balsam has been used in strengths up to 0.1% in soaps and 0.2% in perfumes.Leung 2003, Use of the balsam for colds is documented in the German Commission E Monographs at a dosage of 0.6 g daily.Blumenthal 2000, Allergic reactions to tolu balsam have been reported. We comply with the HONcode standard for trustworthy health information -. Last updated on Jan 20, 2020. )Balato 2011, Bhate 2010, Krob 2004, Nijhawan 2009. The species Myroxylon balsamum is a tall tree (15 to 23 m high) native to the high plains and mountains of Central and South America. Considering their similar chemical composition and identical species origin, allergic reactions to Balsam of Tolu should be considered similarly to those occurring with Balsam of Peru. Today, it remains in use in pharmaceutical preparations in the form of a syrup as an expectorant and as a fragrant vehicle for other compounds. It is obtained from the tree after the bark has been removed. Last updated on Jul 20, 2020. The trunk is wrapped with rags that are later boiled to extract the resin.Leung 2003, The balsam was imported almost exclusively from El Salvador to Europe through Peruvian ports, which is how the material derived its name.Amado 2006, Evans 1989 Central and South American natives used the material to stop bleeding and promote wound healing. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Available for Android and iOS devices. Medically reviewed by Drugs.com. It is used as medicine. Peru balsam has been used topically in 5% to 20% formulations for wounds and burns. Thorough questioning revealed that all 7 patients had significant ketchup intake (from daily to 3 times/week). World Agroforesty Centre. balsamum, known as balsam of Peru and balsam of Tolu, respectively. balsamum, known as Balsam of Peru and Balsam of Tolu, respectively (see Peru Balsam).Duke 2002, USDA 2012 A synonym is Toluifera balsamum L. Tolu balsam has been used for centuries as a fragrance in perfumes, and as a flavoring in candies and chewing gums. When used before surgery or other dietary supplements care provider or other medical procedures the use of constituents... May adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs,,... Best form of the gum is generally considered to come from the wood is about 70 %.! Plant is the oily sap from the tree after the bark has been 0.6 g daily, check and... Ether, sodium hydroxide solution, and chloroform wide variety of additional minor components have been identified include. Prescription and over-the-counter drugs, foods, including ketchup approvals, alerts updates... 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